Acetaminophenol Synthesis Lab Report

The absorbance and the maximum wavelength of all eight standard solutions were determined using the same spectrophotometer in this section. First, approximately 3 mL of each solution was added into a cuvette using a plastic pipette. The solution was added until the level reached the frosty part of the cuvette and any bubbles were dislodged by gently tapping the cuvette against a hard surface. Then, a Kimwipe was used to clean the exterior of the cuvette. Once cleaned, the cuvette was transported by only holding the top edges.

Trichromatic Ultraviolet and ROYGBV (visible light) Infrared and visible – small heat

We then found the maximum wavelength at which each dye displayed the maximum absorbance based on the peaks in each curve. For allura red, this peak occurred at 500 nm. For sunset yellow, this peak occurred at 480 nm. Using our data from the calibration curve (Table 2), we were able to find the extinction coefficient using Beer’s Law. Beer’s Law states .

The difference in this chemical and physical properties will aid in their separation. Processes like solubility, gravitational filtration and recrystallization will be used to separate the substances present in Panacetin. The melting and boiling point of the substances will help in concluding on which of these compounds will be presented at the end of experiment. Procedure and observation The Panacetin content was weighed approximately 3.0493g and transferred to the Erlenmeyer flask; 75ml of dichloromethane (CH¬2CL2) was added to the content. The dichloromethane (CH2Cl2) dissolved the sucrose, leaving the active unknown agent and aspirin behind.

Since, acetaminophen takes away pain acetaminophen is a drug that can be used and sold. Acetaminophen is a product that people can sell to make money and that assists them economically. Or, acetaminophen can be used so that people can go to work, For example, say that someone has a pain somewhere like a headache and that person does not believe that they are able to go to work then they can take acetaminophen feel better and be able to go to work and get paid. Acetaminophen is a useful molecule because it is a great tool to kill pain and stay afloat

The purpose of this experiment was to understand the pharmacokinetics of the drug acetaminophen within the body, specifically focusing on its partition coefficient, drug protein interaction and its bioavailability through various form of administration. The bioavailability of the drug was determined to be 100% for IV because the drug is injected directly into the systemic circulation in its active form and this is also visible on Figure 4, where the initial concentration of drug is much higher than in PO and IP. For PO and IP administration, the bioavailability was determined to be 72.6% and 39.1%, respectively. This makes sense because both of these type of administration involve the first-pass effect where a portion of the drug is metabolized by peripheral organs, especially the liver in this case, and therefore the amount of active drug reaching the circulation is less. PO administration, however has a much higher content reaching the circulation than IP, because the IP route involves passing through the whole gastrointestinal tract before being absorbed in the liver while the IP route injects the drug into the

Light absorption occurs when atoms or molecules take up the energy of a light and reduces the transmission of light. The absorbance will increase with an increase in concentration while the transmittance will decrease with an increase in

Pediatric dosing for Acetaminophen for child < 60 kg is 10 to 15 mg/kg/dose orally every 4-6 hours. A maximum dose of 75 mg/kg/day in infants. This medication is contraindicated if the child has active or severe hepatic disease.

According to Google, the lethal dosage for acetaminophen is 10 grams. As I scanned the painkiller aisle in CVS for the least expensive option that would do the job, my eyes rested on a small bottle of extra-strength Tylenol. 24 tablets, the bottle read, 500 milligrams each. I quickly worked that out in my head to be 12 grams.

Vicodin contains the combination of acetaminophen and hydrocodone. Hydrocodone is a a drug that acts on the nervous system to receive pain. Acetaminophen is a little less stronger pain reliever that increases the effect of hydrocodone. Vicodin is prescribed for moderate to sever pain. They should only be prescribed for abrupt, short-term, or pain caused by injury or surgery.

Lab Report 5: Acetylsalicylic Acid (Aspirin) Synthesis Name: Divya Mehta Student #: 139006548 Date Conducted: November 19th 2014 Date Submitted: November 26th 2014 Partner’s Name: Kirsten Matthews Lab Section: Wednesday 2:30 L9 IAs Name: Brittany Doerr Procedure: For the procedure, see lab manual (CH110 Lab Manual, Fall 2014) pages 96-98. Wilfrid Laurier University Chemistry Department. Fall 2014. Acetylsalicylic Acid (Aspirin) Synthesis.

The actual ingredients in unknown A was acetaminophen and cornstarch. The actual ingredients in unknown B was acetaminophen, acetylsalicylic acid, caffeine, and

Although the value of the isolated caffeine is nearly double that of the pure caffeine, it appears that caffeine was separated from Excedrin, but the sample was not pure. It still had other analgesics present. This is concluded from the location

The main objective of this experiment was the formation of phenacetin from the synthesis of acetaminophen. This was done through a chemical reaction known as the Williamson ether synthesis using techniques of refluxing, vacuum filtration and recrystallization incorporating a mixed solvent system. A further objective of this experiment was to study the formation of the product (phenacetin). Such validation was completed by using techniques for determining the melting point, calculating percent yield, and IR (infrared spectroscopy) of the resultant product.

An organ bath experiment was conducted to investigate the effect of agonist, histamine on guinea pig ileum (GPI) and how the antagonists, mepyramine and SIPBSDrug A affect the GPI’s response (smooth muscle contractions). A GPI simulation was conducted to compare the potencies and nature of antagonists against histamine. The control Rmax and EC50 of histamine without antagonist were 16.49gms and 2.093 x 10-7M respectively. The concentration-response curves were shifted to right parallelly and EC50 increased while Rmax remained constant when mepyramine or SIPBSDrug A was added. Besides, both antagonists showed linear graphs in Schild plot, indicating that they acted as reversible competitive antagonists.