Motiva Reaction Lab Report

Therefore,

The following lab period the solid was weighed (0.0483 g) and percent yield was calculated (65.5%) with the limiting reagent being tetraphenylcyclopentadienone. The melting point was determined. The first melting point was 204-204.9 °C and the second melting point was 215.6-215.9°C. Finally, an infrared spectroscopy was obtained for the

Therefore,

Therefore,

Such a change may include the use of a stronger base, acting to be attack the water molecules at a much faster rate than the amides of dabigatran can undergo hydrolysis. In order provide a safe way of binding a stronger base to dabigatran to reverse its affects, amino acids already found within the human body may be of use. Amino acids such as proline, leucine, and alanine all contain amine, NH2, functional groups. If one of the amino acids provided was discovered to have binding capabilities, perhaps in a slightly altered form, to dabigatran, the strong basic capabilities of the amines would act to deprotonate water at a very fast rate. The aftereffects of such a reaction may be potentially hazourdous, as the byproduct would be NH3, but that still presents an interesting method of preventing

Paragraph 1 Compare and contrast the crystal structures and crystal chemistry of quartz, α-FePO4 and β- FePO4. Crystal structure is defined as the orderly arrangement of atoms, ions or molecules in both liquid and solid states. Quartz has a trigonal crystal system and a six-sided prism with six-sided pyramids at each end.

The yellow solution containing the reactants was slowly poured into the beaker containing the cold water and the acid in order to cause the precipitation of the alcohol, 9-fluorenol and to destroy (hydrolyzed) the unreacted excess sodium borohydride. Subsequently, the white precipitate was vacuum filtered and washed twice with 20.0 ml portions of distilled cold water by pouring the liquid into the Buchner Funnel during filtration. It was necessary to wash the alcohol prior to recrystallization considering that the C-OH bond is easily broken by the formation of a stable and benzylic carbocation that favors the synthesis of difluorenyl ether. Finally, before the purification by recrystallization of the obtained product, the white solid alcohol was allowed to dry over a period of a

Two small additional peaks at δ = 0.8 and δ = 1.6 were found may be due to impurities present. 1H-NMR spectrum of PHA isolated from glucose or molasses media indicated characteristic signals of PHB, namely a doublet at 1.26 ppm, which is attributed to the methyl (CH3) group coupled to one proton while a doublet of quadruplet at 2.51 ppm due to the methylene (CH2) group adjacent to an asymmetric carbon atom bearing a single proton. The third signal at 5.25 ppm, which was attributed to the methine (CH) group. 1H-NMR is a very sensitive method for determining the domain size and miscibility, which is difficult to identify by conventional microscopic or thermal analysis (Kichise et al., 2002).The values of the chemical shifts as well as the assignments of the 1H-NMR signals, which appeared in the spectra are in agreement with results obtained by Kichise et al.

To further evaluate the binding regions within the binding site, an aromatic CH probe was used to locate hydrophobic regions (Patrick, 2013, p. 407). It was found that the pteridine ring of CB 3717 formed its hydrogen bond within a hydrophobic region. Based on this, the researchers determined that a naphthalene ring could be a reasonable replacement for the pteridine group, with ample room to include a substituent that could recreate the hydrogen bonding

Not protein chemistry 2007 Not protein chemistry Not protein chemistry 2008 Not protein chemistry for the discovery and development of the green fluorescent protein, GFP To: Osamu Shimomura, Martin Chalfie, Roger Y. Tsien GFP is glowing marker which is tagged to certain proteins to study the chemical interactions for example nerve cell damage in Alzheimer disease. 2009 for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase To: Elizabeth H. Blackburn, Carol W. Greider, Jack W.

The reactions between acids and bases of solutions are extremely important in a number of different contexts such as industrial, environmental, and biological. Acid reflux is common in many people and it causes heartburn; Antacids help temporarily alleviate this. This investigation helps

Table 4 shows the results of docking for the active compounds. The Glide XP Gscores and glide energies clearly indicate that the most active compounds in the study exhibited significant binding affinities towards the wild (Glide energy range -58.11 kcalmol-1 to -44.32 kcalmol-1) and quadruple mutant (Glide energy range -56.14 kcalmol-1 to -43.74 kcalmol-1) PfDHFR-TS structures and the energy ranges are comparable to that of reference compounds (pyrimethamine, cycloguanil and WR99210) and the native substrate of DHFR dihydrofolate (Table 4). < Insert Table 4

and NMR spectra were recorded in CD3OD and CDCL3 using a Bruker WM 500 spectrometer at room temperature [500 MHz (1 H NMR) and 125 MHz (13C NMR)]. From the results of spectral analysis found;9-hexanoyl-3-(2-hydroxypropyl)-6a-methyl-9,9a-dihydro-6H-furo[2,3-h]isochromene-6,8(6aH)-dioneand4-[2,4-dihydroxy-6-(3-hydroxybutanethioyloxy)-3methylphenyl]-3,4-dihydroxy-3,6-dimethylheptanoic acid. These pigments may have been better to used as colorants in food industry (Campoy S et al.

Fluorite has interesting deavage habits. The perfect deavage parallel to the octaheadral faces can sometimes be peeled off to smooth out a crystal into a perfect octahedron. Many crystals, especially larger ones, have their edges or sections chipped off because of the deavage. Fluorite is

Abstract The unknown concentration of benzoic acid used when titrated with standardized 0.1031M NaOH and the solubility was calculated at two different temperatures (20◦C and 30◦C). With the aid of the Van’t Hoff equation, the enthalpy of solution of benzoic acid at those temperatures was determined as 10.82 KJ. This compares well with the value of 10.27KJ found in the literature.